Clinical evaluation of the therapeutic effects of atelocollagen absorbable punctal plugs

نویسندگان

  • Kaori Hirai
  • Yoji Takano
  • Eiichi Uchio
  • Kazuaki Kadonosono
چکیده

PURPOSE To evaluate the therapeutic effects of atelocollagen absorbable punctal plugs. METHOD Seventy-four eyes in 37 patients with dry eye disease (DED) underwent punctal plug occlusion using atelocollagen plugs and were followed up for 24 weeks. Subjective symptoms were evaluated using the ocular surface disease index (OSDI) questionnaire. Ocular surface disease parameters, including the Schirmer test, phenol red thread test, tear break-up time (TBUT), and fluorescein and Rose Bengal staining, were recorded before and 1, 4, 8, 16, and 24 weeks after treatment. RESULTS In comparison with the pretreatment data, the subjective symptoms and ocular surface disease parameters showed significant improvement after atelocollagen punctal occlusion. The average time of relapse was 17.4 ± 5.1 weeks. No severe complications occurred, and none of the plugs had to be removed because of local discomfort or epiphora. CONCLUSION Atelocollagen absorbable punctal plugs effectively improved ocular surface disorders in DED. These plugs are a safe and effective alternative in the treatment of DED.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Lacrimal duct occlusion for the treatment of dry eye.

The most widespread treatment for dry eyes in clinical practice is an instillation containing artificial tear fluid. When an instillation does not ameliorate dry eye, we use punctal plugs. The insertion of punctal plugs is an eminent curative that positively improves the corneal and conjunctival epithelial disorders and the amount of lacrimal fluid accumulated in the conjunctival sac. We shall ...

متن کامل

Tarsorrhaphy and lacrimal occlusion

Corneal hydration and protection can be achieved through increased lubrication or decreased evaporation. Hence, an important therapeutic strategy to corneal desiccation involves occlusion of the lacrimal drainage system in order to decrease tear outflow and provide additional ocular surface hydration. Three general approaches can be used: temporary, reversible, or permanent occlusion of the lac...

متن کامل

[Perforated punctum plugs in treatment lacrimal punctal stenosis].

PURPOSE Retrospective evaluation of treatment of epiphora due to punctal stenosis with application of perforated plugs as well as evaluation of complications. MATERIAL AND METHOD There were inserted perforated plugs into inferior lacrimal puncta to twelve patients with epiphora due to proximal stenosis in efferent lacrimal ducts. Their size were predeterminated by caliper measuring. Patients ...

متن کامل

Ampullary pyogenic granuloma as a complication of lacrimal plug migration.

We present a patient with ampullary pyogenic granuloma caused by spontaneous migration of a silicone lacrimal plug. A 43-year-old woman with severely dry eyes was treated with non-absorbable silicone punctal plugs insertion in both superior and inferior puncta. Irritation and purulent discharge gradually developed 3 weeks after implantation. A pink, fleshly ampullary lesion over the left superi...

متن کامل

Comprehensive Review of the Literature on Existing Punctal Plugs for the Management of Dry Eye Disease

Numerous designs of punctal and canalicular plugs are available on the market. This variety presents challenges to ophthalmologists when choosing punctal plugs for the management of various ocular conditions. The aim of this literature review is to provide a classification system for lacrimal occlusive devices based on their location and duration of action as well as to identify different chara...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2012